Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255272 | 0.87 | LTA4H (0.67) | SCN9ALTA4HTSHRFFAR1EPHX2 | |
| SCHEMBL10686173 | 0.87 | LTA4H (0.65) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| SCHEMBL2856821 | 0.87 | LTA4H (0.65) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| SCHEMBL3681820 | 0.87 | LTA4H (0.65) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| Phosphine SCHEMBL23466364 | 0.85 | LTA4H (0.63) | SCN9ALTA4HTSHRFFAR1EPHX2 | |
| Ammonia Solution, Strong SCHEMBL4263312 | 0.85 | LTA4H (0.63) | SCN9ALTA4HTSHRFFAR1EPHX2 | |
| SCHEMBL9190364 | 0.85 | LTA4H (0.71) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| SCHEMBL21921128 | 0.85 | LTA4H (0.71) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| Biphenyl SCHEMBL10838288 | 0.85 | LTA4H (0.71) | LTA4HTSHRBCL2L1MCL1SCN4A | |
| SCHEMBL28436317 | 0.85 | LTA4H (0.61) | LTA4HTSHRBCL2L1MCL1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |