Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732530 | 0.89 | NPC1 (0.69) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12259177 | 0.85 | L3MBTL1 (0.56) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8958776 | 0.84 | NPC1 (0.55) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6201913 | 0.82 | NPC1 (0.64) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14405820 | 0.80 | GAA (0.59) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11803183 | 0.80 | MAPT (0.78) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20876059 | 0.80 | KMT2A (0.88) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL9786970 | 0.80 | MAPT (0.74) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1107148 | 0.79 | GAA (0.70) | NPC1KMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15908103 | 0.79 | GAA (0.62) | NPC1KMT2AMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |