Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433645 | 0.89 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL7940696 | 0.84 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL9786970 | 0.79 | MAPT (0.74) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL5454957 | 0.78 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8321862 | 0.76 | GAA (0.64) | SMN1; SMN2MAPTHPGDPPARG | |
| SCHEMBL9787068 | 0.76 | LMNA (0.80) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL7946523 | 0.76 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL28959509 | 0.75 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL436174 | 0.75 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL1068092 | 0.75 | MAPT (0.69) | NPC1RAB9ASMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565606-A | Synthesis of peptide aminoalkylamides and peptide hydrazides by the solid-phase method | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |