SCHEMBL794071

SCHEMBL794071

CC(C)(C)c1cccc(C=O)c1[N]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
ALOX12 P18054 1/20 0.41
CA2 P00918 2/20 0.40
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
ERN1 O75460 4/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
TLR2 O60603 1/20 0.35
TLR1 Q15399 1/20 0.35
TLR6 Q9Y2C9 1/20 0.35
CA1 P00915 1/20 0.35
TRIM24 O15164 2/20 0.34
TRIM33 Q9UPN9 2/20 0.34
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536090 0.79 LMNA (0.55) TDP1MEN1LMNATHRBBLM
SCHEMBL138253 0.78 CA2 (0.55) TDP1LMNAALOX12CA2ALDH1A1
SCHEMBL17261584 0.78 TDP1 (0.42) TDP1MEN1LMNATHRBBLM
SCHEMBL173039 0.76 ALOX12 (0.62) TDP1MEN1LMNATHRBBLM
SCHEMBL15428022 0.76 LMNA (0.41) TDP1MEN1LMNATHRBBLM
SCHEMBL31587806 0.76 ALOX12 (0.62) TDP1MEN1LMNATHRBBLM
SCHEMBL28479243 0.76 TDP1 (0.41) TDP1MEN1LMNATHRBBLM
SCHEMBL15427843 0.76 ALOX12 (0.38) TDP1MEN1LMNATHRBBLM
Formaldehyde SCHEMBL28869544 0.75 TDP1 (0.50) TDP1MEN1LMNATHRBBLM
SCHEMBL2489642 0.73 CA2 (0.58) TDP1MEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616424-B1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2015-08-26 EP disclosed
EP-2616424-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2013-07-24 EP disclosed
WO-2012034930-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 WO disclosed