Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LIG1 | P18858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576927 | 0.92 | ALDH1A1 (0.61) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL8771948 | 0.90 | ALDH1A1 (0.58) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21679527 | 0.87 | LMNA (0.49) | MEN1KMT2ARAB9ALMNAMAPT | |
| Benzophenone SCHEMBL27537831 | 0.84 | MEN1 (0.86) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL9400453 | 0.84 | MEN1 (0.86) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7938553 | 0.84 | MEN1 (0.86) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL124916 | 0.84 | MEN1 (0.86) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7935392 | 0.84 | LMNA (0.51) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL27432711 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2ARAB9ALMNAHPGD | |
| SCHEMBL487058 | 0.82 | CA12 (0.48) | MEN1KMT2ARAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |