SCHEMBL487058

SCHEMBL487058

[O-][S+](c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
GLA P06280 1/20 0.48
ESR1 P03372 11/20 0.46
ESR2 Q92731 9/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
KMT2A Q03164 2/20 0.41
LTA4H P09960 1/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfinyl)Benzene SCHEMBL28482857 0.92 CA12 (0.58) CA12CA1CA2CA3CA4
SCHEMBL18338 0.89 CA1 (0.50) CA12CA1CA2CA3CA4
SCHEMBL7940643 0.89 MMP3 (0.65) CA12CA1CA2CA3CA4
SCHEMBL11022392 0.87 ALOX15 (0.47) CA12CA1CA2CA3CA4
SCHEMBL12336893 0.87 TDP1 (0.35) CA12CA1CA2CA3CA4
(Phenylsulfinyl)Benzene SCHEMBL43199 0.84 TDP1 (0.37) CA12CA1CA2CA3CA4
SCHEMBL7937346 0.82 ALDH1A1 (0.44) CA12CA1CA2CA3CA4
SCHEMBL28145577 0.82 ESR1 (0.58) CA12CA1CA2CA3CA4
SCHEMBL7940723 0.82 MEN1 (0.63) CA12CA1CA2CA3CA4
(Phenylsulfinyl)Benzene SCHEMBL29061945 0.81 CA2 (0.33) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4066619-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1978-01-03 US claimed
EP-3395857-B1 POLYMER CONJUGATE OF SULFOXIDE DERIVATIVE-COORDINATED PLATINUM(II) COMPLEX NIPPON KAYAKU KK (JP) 2021-05-26 EP disclosed
CN-108473676-B Polymer conjugate of sulfoxide derivative coordination platinum (II) complex 日本化药株式会社 2021-04-27 CN disclosed
US-10946028-B2 Polymer conjugate of sulfoxide derivative-coordinated platinum(II) complex NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2021-03-16 US disclosed
US-20180369254-A1 Polymer Conjugate Of Sulfoxide Derivative-Coordinated Platinum(II) Complex NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-12-27 US disclosed
EP-3395857-A1 POLYMER CONJUGATE OF SULFOXIDE DERIVATIVE-COORDINATED PLATINUM(II) COMPLEX Nippon Kayaku Kabushiki Kaisha (JP) 2018-10-31 EP disclosed
CN-102391203-A Intermediate of 6-substituted-1-methyl-1-h-benzimidazole derivative and method for producing same SANKYO CO 2012-03-28 CN disclosed
US-8106079-B2 Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same SANKYO COMPANY, LIMITED (JP) 2012-01-31 US disclosed
CN-101068770-B Process for producing 6-substituted-1-methyl-1-H-benzimidazole derivative and synthetic intermediate therefor SANKYO CO 2012-01-04 CN disclosed
US-7816552-B2 Intermediate of 6-substituted 1-methyl-1-H-benzimidazole derivative and method for producing same SANKYO COMPANY, LIMITED (JP) 2010-10-19 US disclosed
EP-1172393-B1 CURABLE RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND COATED OBJECT MADE WITH THE SAME DAICEL CHEM (JP) 2007-10-31 EP disclosed
EP-1798216-A1 INTERMEDIATE OF 6-SUBSTITUTED-1-METHYL-1-H-BENZIMIDAZOLE DERIVATIVE AND METHOD FOR PRODUCING SAME Sankyo Company, Limited (JP) 2007-06-20 EP disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0443533-A2 Positive photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
EP-0229626-B1 POLYARYLENE SULFIDE WITH A WELL-DEFINED FUSION VISCOSITY BAYER AG (DE) 1990-06-20 EP disclosed
US-4771120-A Polyarylene sulphide capped with monophenol compound BAYER AKTIENGESELLSCHAFT (DE) 1988-09-13 US disclosed
EP-0229626-A1 Polyarylene sulfide with a well-defined fusion viscosity BAYER AG (DE) 1987-07-22 EP disclosed
US-4066619-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1978-01-03 US disclosed
US-4066619-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10946028-B2 Polymer conjugate of sulfoxide derivative-coordinated platinum(II) complex FPGS, GSS, SCLY CA12 869/4885CA1 678/4885CA2 3550/4885
US-20180369254-A1 Polymer Conjugate Of Sulfoxide Derivative-Coordinated Platinum(II) Complex FPGS, GSS, SCLY CA12 869/4885CA1 678/4885CA2 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.