Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965964 | 0.84 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL5966154 | 0.83 | FKBP1A (0.45) | FKBP1A | |
| SCHEMBL7939535 | 0.78 | FKBP1A (0.36) | FKBP1ASMN1; SMN2RAB9ALMNAKDM4E | |
| SCHEMBL5966105 | 0.77 | FKBP1A (0.39) | FKBP1ALMNA | |
| SCHEMBL5700583 | 0.74 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL7940812 | 0.70 | FKBP1A (0.60) | FKBP1AKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL28299649 | 0.70 | CYP3A4 (0.44) | LMNA | |
| SCHEMBL5966221 | 0.65 | FKBP1A (0.36) | FKBP1AKMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3397276 | 0.64 | FKBP1A (0.51) | FKBP1A | |
| SCHEMBL5834349 | 0.64 | FKBP1A (0.51) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777478-B1 | INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GUILFORD PHARM INC (US) | 2001-11-07 | — | — | EP | claimed |