SCHEMBL28299649

SCHEMBL28299649

CCC(c1ccccc1)C1CCCN1C(=O)N1CCCC1C(CC)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP1A2 P05177 1/20 0.44
KCNK3 O14649 5/20 0.42
DPP4 P27487 2/20 0.42
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
DPP8 Q6V1X1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6989534 0.80 FABP4 (0.44) CYP3A4CYP2D6CYP1A2KCNK3
SCHEMBL28299650 0.77 CYP3A4 (0.39) CYP3A4CYP2D6CYP1A2HTTLMNA
SCHEMBL16635365 0.75 CCL5 (0.40) KCNK3
SCHEMBL9776981 0.74 ALDH1A1 (0.46) DPP4DPP8
SCHEMBL18735973 0.72 POLB (0.46) CYP2D6DPP4HTT
SCHEMBL5965964 0.71 FKBP1A (0.39) CYP3A4CYP2D6CYP1A2DPP4DPP8
SCHEMBL3536343 0.71 CYP2D6 (0.50) CYP3A4CYP2D6CYP1A2HTTLMNA
Hydrochloric Acid SCHEMBL10985140 0.71 CYP3A4 (0.49) CYP3A4CYP2D6CYP1A2HTT
SCHEMBL5966154 0.71 FKBP1A (0.45)
SCHEMBL9873550 0.70 ALDH1A1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636947-B N- heteroaryl (thio) carbonyl -2- (Benzocycloalkene -1- base) cyclammonium and its purposes as fungicide 拜耳作物科学股份公司 2019-05-07 CN disclosed