Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938157 | 0.85 | ESR2 (0.50) | LMNAMAPTHPGDESR1ESR2 | |
| SCHEMBL7937365 | 0.83 | LTA4H (0.48) | LMNAMAPTHPGDELANEMAPK1 | |
| SCHEMBL5541822 | 0.81 | ESR1 (0.58) | LMNAMAPTHPGDHTTESR1 | |
| SCHEMBL3418004 | 0.81 | ELANE (0.66) | LMNAMAPTHPGDHTTESR1 | |
| SCHEMBL7937271 | 0.79 | MEN1 (0.64) | ESR1ESR2ELANEMAPK1MEN1 | |
| SCHEMBL7938528 | 0.79 | ESR2 (0.52) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL3365915 | 0.78 | CA1 (0.54) | PKMSRD5A2PPARGPPARAFABP2 | |
| SCHEMBL6520817 | 0.78 | ALDH1A1 (0.41) | LMNAMAPTHPGDELANEMAPK1 | |
| SCHEMBL31012104 | 0.77 | MAPT (0.71) | LMNAMAPTHPGDHTTESR1 | |
| SCHEMBL10486226 | 0.77 | MAPT (0.71) | LMNAMAPTHPGDHTTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |