Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PIR | O00625 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916549 | 0.81 | CCR1 (0.32) | RAB9ACCR1CCR5EDNRBEDNRA | |
| SCHEMBL29584480 | 0.81 | RAB9A (0.33) | RAB9ACCR1CCR5MAP3K14GAA | |
| SCHEMBL24423806 | 0.81 | RAB9A (0.33) | RAB9ACCR1CCR5MAP3K14GAA | |
| SCHEMBL10286059 | 0.81 | MAP3K14 (0.47) | RAB9ACCR1CCR5MAP3K14GAA | |
| SCHEMBL25832673 | 0.78 | EDNRB (0.33) | EDNRBEDNRA | |
| SCHEMBL12891533 | 0.71 | MAP3K14 (0.38) | RAB9AMAP3K14P2RX7SMN1; SMN2HTT | |
| SCHEMBL12891532 | 0.71 | MAP3K14 (0.38) | RAB9AMAP3K14P2RX7SMN1; SMN2HTT | |
| SCHEMBL10297720 | 0.71 | MAP3K14 (0.38) | RAB9AMAP3K14P2RX7SMN1; SMN2HTT | |
| SCHEMBL10238798 | 0.68 | HTR2A (0.34) | RAB9ACCR1CCR5 | |
| SCHEMBL2437286 | 0.67 | MBOAT4 (0.40) | RAB9ACCR1CCR5GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130384-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110130384-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2298731-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009157196-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130384-A1 | AMIDE COMPOUND | GPR52, CNR2, ARRB1 | RAB9A 3900/4885CCR1 465/4885CCR5 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.