SCHEMBL7941153

SCHEMBL7941153

COc1ccc2c(c1)C([Zr](C)C)c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.44
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
CYP1A2 P05177 3/20 0.41
CYP2A6 P11509 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP2C8 P10632 1/20 0.41
CYP4B1 P13584 1/20 0.41
CYP2B6 P20813 1/20 0.41
CYP3A5 P20815 1/20 0.41
CYP2A7 P20853 1/20 0.41
CYP3A7 P24462 1/20 0.41
CYP2F1 P24903 1/20 0.41
CYP2C18 P33260 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103508 0.80 GPR3 (0.46) GPR3CYP1A2CYP2D6HTR2AMEN1
SCHEMBL28482076 0.77 ELANE (0.41) GPR3CYP1A2CYP2A6GAAMAPT
SCHEMBL9449351 0.76 HRH3 (0.51) GPR3CYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL30818407 0.76 GPR3 (0.46) GPR3ABL1ABCB1BCRCYP1A2
Hydrochloric Acid SCHEMBL7201366 0.75 GPR3 (0.45) GPR3ABL1ABCB1BCRCYP1A2
SCHEMBL27409851 0.73 CYP1A1 (0.42) CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL8162345 0.72 HTR2A (0.35) GPR3CYP1A2CYP2A6GAAHTR2A
SCHEMBL9449380 0.72 HRH3 (0.55) GPR3ABL1ABCB1BCRCYP1A2
SCHEMBL7945498 0.71 NR3C1 (0.49) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL9449452 0.71 MAPT (0.49) GPR3CYP3A4CYP2C9GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316558-B1 POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN TOSOH CORPORATION (JP) 2001-11-13 US disclosed