Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.42 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7201110 | 0.91 | CYP1A2 (0.46) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7198761 | 0.81 | CA12 (0.46) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL27745820 | 0.81 | CYP1A1 (0.45) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 | |
| SCHEMBL9449351 | 0.77 | HRH3 (0.51) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 | |
| SCHEMBL30818407 | 0.77 | GPR3 (0.46) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 | |
| Ethane SCHEMBL8174121 | 0.77 | GPR3 (0.46) | GPR3CYP1A2CYP2D6HTR2AMEN1 | |
| Hydrochloric Acid SCHEMBL540484 | 0.77 | GPR3 (0.44) | GPR3CYP1A2CYP2D6HTR2AMEN1 | |
| SCHEMBL7941153 | 0.75 | GPR3 (0.44) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7944464 | 0.74 | GPR3 (0.42) | GPR3CYP1A2CYP2D6HTR2AMEN1 | |
| SCHEMBL9449380 | 0.73 | HRH3 (0.55) | GPR3CYP1A2CYP2A6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942006-B1 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORP (JP) | 2003-06-04 | — | — | EP | disclosed |