Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466245 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNAMAPTBLM | |
| SCHEMBL8583778 | 0.83 | FDPS (0.50) | MAPTFDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL10645052 | 0.83 | FDPS (0.50) | MAPTFDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL10646888 | 0.83 | FDPS (0.50) | MAPTFDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL8581734 | 0.83 | MAPT (0.55) | MAPTFDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL8584175 | 0.81 | MAPT (0.58) | MAPTFDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL7941318 | 0.81 | BLM (0.47) | ALDH1A1TDP1LMNABLMFDPS | |
| SCHEMBL11309386 | 0.74 | GRIN2D (0.33) | TDP1LMNABLMGRIN2DGRIN3B | |
| SCHEMBL19761997 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNABLMFDPS | |
| SCHEMBL2304432 | 0.73 | KDM4C (0.39) | ALDH1A1TDP1LMNABLMFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026149-A1 | DIMETHYL-(3,3-DIFLUORO-2,2-DIHYDROXYHEPTYL)PHOSPHONATE AND PROCESSES FOR ITS PREPARATION | APOTEX PHARMACHEM INC. (CA) | 2013-02-28 | — | — | WO | disclosed |
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0455899-B1 | Prostaglandin I analogue | R TECH UENO LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0469782-B1 | Treatment of cataract with prostacyclin compounds | R TECH UENO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5428062-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5235072-A | 2-OXABICYCLO(2,2,1)HEPTANE DERIVATIVES AND PHARMACEUTICAL | SCHERING AKTIENGSELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0284180-A1 | Prostaglandins E and anti ulcers containing same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4532236-A | Certain prostacyclins and their blood-pressure-lowering and thrombocyte-aggregation-inhibiting compositions and methods | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| US-4410720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4246426-A | USEFUL IN INDUCING LABOR, TERMINATING PREGNANCY, TREATING GASTRIC HYPERACIDITY, WITH CARDIOVASCULAR AND BRONCHODILATOR EFFECTS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4246402-A | CARDIOVASCULAR AGENTS AND OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4227019-A | CARDIOTONIC AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226985-A | CARDIOVASCULAR AGENTS, OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4059576-A | CARDIOVASCULAR, OXYTOCICS | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4052446-A | OXYTOCICS, CARDIOVASCULAR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4036871-A | CARDIOVASCULAR AGENTS, LABOR INDUCERS, ABORTION | HOFFMANN-LA ROCHE INC. (US) | 1977-07-19 | — | — | US | disclosed |