SCHEMBL7941505

SCHEMBL7941505

C=CC(=O)OC(C)(OCC)OC(CC)(OC(C)(OCC)OC(=O)C=C)OC(C)(OCC)OC(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18166514 0.90 TSHR (0.37) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1070261 0.86 TSHR (0.39) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2332616 0.81 TSHR (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL4904711 0.80 THRB (0.40) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28797570 0.79 THRB (0.39) THRBTSHRHPGDALDH1A1TP53
SCHEMBL10592331 0.79 ALDH1A1 (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL7771137 0.78 TSHR (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1706295 0.76 THRB (0.44) THRBTSHRHPGDALDH1A1TP53
SCHEMBL27951416 0.75 THRB (0.37) THRBTSHRHPGDALDH1A1TP53
SCHEMBL5489087 0.74 TSHR (0.39) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863128-B1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLATE ESTERS, COMPOSITIONS, LOW-REFRACTION MATERIALS, AND ANTIREFLECTION FILMS NOF CORP (JP) 2001-11-21 EP disclosed
US-6254973-B1 WEAR RESISTANCE NOF CORPORATION (JP) 2001-07-03 US disclosed
US-6087010-A PROVIDES COMPOUNDS HAVING SUFFICIENTLY LOW REFRACTIVE INDEX, SUFFICIENTLY HIGH SURFACE HARDNESS, AND ADHESION NOF CORPORATION (JP) 2000-07-11 US disclosed
EP-0863128-A1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLATE ESTERS, COMPOSITIONS, LOW-REFRACTION MATERIALS, AND ANTIREFLECTION FILMS NOF CORPORATION (JP) 1998-09-09 EP disclosed
EP-0820980-A1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLIC ESTERS, FLUOROMONOMER COMPOSITION, MATERIAL WITH LOW REFRACTIVE INDEX, AND LOWLY REFLECTIVE FILM NOF CORPORATION (JP) 1998-01-28 EP disclosed