Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941640 | 0.77 | MAPT (0.47) | ALDH1A1POLBNPC1RAB9AMAPT | |
| SCHEMBL7933019 | 0.75 | RAB9A (0.46) | ALDH1A1POLBNPC1RAB9AMAPT | |
| SCHEMBL11626970 | 0.75 | RAB9A (0.53) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL27804593 | 0.74 | RAB9A (0.56) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL5734991 | 0.73 | ERN1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6231939 | 0.73 | RAB9A (0.60) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL27804595 | 0.72 | RAB9A (0.52) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL30461135 | 0.71 | RAB9A (0.69) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL30461136 | 0.71 | RAB9A (0.69) | ALDH1A1NPC1RAB9AIDO1MAPT | |
| SCHEMBL7354504 | 0.71 | PDE4A (0.42) | ALDH1A1POLBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | claimed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | claimed |