Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736391 | 0.88 | CHRNB2 (0.48) | RAB9ACHRNB2CHRNA5CHRNA4PDE4A | |
| SCHEMBL7381984 | 0.77 | PDE4A (0.47) | RAB9ACHRNB2CHRNA5CHRNA4PDE4A | |
| SCHEMBL7381987 | 0.77 | PDE4A (0.47) | RAB9ACHRNB2CHRNA5CHRNA4PDE4A | |
| SCHEMBL7941636 | 0.75 | ALDH1A1 (0.44) | RAB9AALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2080546 | 0.73 | CHRNB2 (0.66) | RAB9ACHRNB2CHRNA5CHRNA4PDE4A | |
| SCHEMBL7347428 | 0.71 | PDE4B (0.43) | PDE4APDE4DALDH1A1POLBKMT2A | |
| SCHEMBL7347423 | 0.71 | PDE4B (0.43) | PDE4APDE4DALDH1A1POLBKMT2A | |
| SCHEMBL7349164 | 0.71 | PDE4B (0.47) | RAB9APDE4APDE4DALDH1A1POLB | |
| SCHEMBL7944333 | 0.71 | PDE4B (0.47) | RAB9APDE4APDE4DALDH1A1POLB | |
| SCHEMBL7360910 | 0.71 | ALDH1A1 (0.42) | RAB9APDE4APDE4DALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | claimed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | claimed |