Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291191 | 0.77 | SOS2 (0.50) | SOS2CTSBNQO1SRCPTPN11 | |
| SCHEMBL1973272 | 0.76 | SOS2 (0.48) | SOS2CTSBNQO1SRCPTPN11 | |
| SCHEMBL16372364 | 0.76 | SOS2 (0.48) | SOS2CTSBNQO1SRCPTPN11 | |
| SCHEMBL10268214 | 0.76 | SOS2 (0.48) | SOS2CTSBNQO1SRCPTPN11 | |
| SCHEMBL5020165 | 0.75 | CTSB (0.43) | SOS2CTSBNQO1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL16741017 | 0.74 | SOS2 (0.47) | SOS2CTSBNQO1SRCPTPN11 | |
| SCHEMBL2250818 | 0.71 | NQO1 (0.46) | SOS2CTSBNQO1SRC | |
| SCHEMBL13286510 | 0.68 | SOS2 (0.41) | SOS2CTSBNQO1SRC | |
| SCHEMBL8745771 | 0.67 | ESR1 (0.51) | SOS2CTSBNQO1ESR1ESR2 | |
| SCHEMBL906658 | 0.67 | SOS2 (1.00) | SOS2CTSBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |