Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfameter. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | DHFR | P00374 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfameter SCHEMBL11137116 | 0.98 | LMNA (0.97) | LMNAAURKADHFRTSHRHTR6 | |
| Sulfameter SCHEMBL27709233 | 0.98 | LMNA (0.97) | LMNAAURKADHFRTSHRHTR6 | |
| Sulfameter SCHEMBL17593237 | 0.98 | LMNA (0.97) | LMNAAURKADHFRTSHRHTR6 | |
| Sulfameter SCHEMBL28250749 | 0.94 | LMNA (0.89) | LMNAAURKADHFRTSHRHTR6 | |
| Sulfameter SCHEMBL7614372 | 0.90 | LMNA (0.81) | LMNAAURKADHFRTSHRHTR6 | |
| Sulfameter SCHEMBL28121714 | 0.88 | LMNA (0.77) | LMNAAURKADHFRTSHRMEN1 | |
| SCHEMBL23567060 | 0.84 | LMNA (0.73) | LMNATSHRMEN1KMT2ASMN1; SMN2 | |
| Sulfametomidine SCHEMBL13723980 | 0.84 | LMNA (0.70) | LMNAAURKADHFRTSHRHTR6 | |
| SCHEMBL2178392 | 0.84 | LMNA (0.72) | LMNAHTR6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5458103 | 0.83 | LMNA (0.71) | LMNAMEN1KMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5488 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12623994-B2 | Method of preparing heterogeneous linear carbonate using catalyst having excellent solubility | LOTTE CHEMICAL CORPORATION (KR) | 2026-05-12 | — | — | US | claimed |
| US-20260091119-A1 | ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA | CELLIS AG (CH) | 2026-04-02 | — | — | US | claimed |
| EP-4637829-A1 | ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER | Cellis Sp. z o.o. ([Ltd.] (PL) | 2025-10-29 | — | — | EP | claimed |
| EP-4630446-A1 | ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF | Dynamic Cell Therapies, Inc. (US) | 2025-10-15 | — | — | EP | claimed |
| EP-4630043-A1 | IMMUNE-ACTIVATING COMPLEXES | Dynamic Cell Therapies, Inc. (US) | 2025-10-15 | — | — | EP | claimed |
| EP-4587062-A1 | ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA | Cellis AG (CH) | 2025-07-23 | — | — | EP | claimed |
| CN-115950926-B | For sulfadimethoxy Electroluminescence for pyrimidine detection chemiluminescent aptamer sensor and detection method | 重庆医科大学 | 2025-06-24 | — | — | CN | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-20250160275-A1 | COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-05-22 | — | — | US | claimed |
| EP-4178637-B1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | HOLLISTER INC (US) | 2025-05-14 | — | — | EP | claimed |
| EP-0358107-A2 | Process for the preparation of pharmaceutical tablets | BASF Aktiengesellschaft (DE) | 1990-03-14 | — | — | EP | claimed |
| US-4801460-A | N-VINYLPYRROLIDONE POLYMER BINDER | BASF AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | claimed |
| EP-0255100-A2 | Use of trimetrexate and its salts for the preparation of pharmaceutical compositions for treating infections of the mycobacterium-avium-intracellulare complex | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | claimed |
| CN-87103409-A | Preparation of solid pharmaceutical dosage forms | — | 1987-12-09 | — | — | CN | claimed |
| EP-0240904-A2 | Process for the preparation of solid pharmaceutical forms | BASF Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | claimed |
| US-4599416-A | Process for the preparation of aqueous solutions of potentiated sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | claimed |
| US-4532245-A | Pharmaceutical compositions | HOFFMANN-LA ROCHE INC. (US) | 1985-07-30 | — | — | US | claimed |
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4110848-A | INTRAOCULAR LENS FOR IMPLANTATION INTO THE POSTERIOR CHAMBER OF A HUMAN EYE | Jensen, Ronald P. (US) | 1978-09-05 | — | — | US | claimed |
| US-3994027-A | Prepupillary lens for implanting in a human eye | CALIFORNIA INTRAOCULAR LENS CORPORATION (US) | 1976-11-30 | — | — | US | claimed |