Nitrobenzene

Nitrobenzene

SCHEMBL7941791

C=CC(COC(C)=O)c1ccc(C)cc1O.CC(C)C(=O)O.O=[N+]([O-])c1ccccc1

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 5/20 0.35
ITGB7 P26010 5/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SRC P12931 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GLO1 Q04760 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
G6PD P11413 1/20 0.33
TRPA1 O75762 1/20 0.33
LMNA P02545 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzene SCHEMBL7948017 0.95 MEN1 (0.35) ITGA4ITGB7MEN1KMT2AALDH1A1
Fluorobenzene SCHEMBL7948168 0.86 SRC (0.36) MEN1KMT2ASRCALDH1A1HTT
Fluorobenzene SCHEMBL7951732 0.81 KMT2A (0.37) MEN1KMT2ASRCALDH1A1HTT
Anisole SCHEMBL7949773 0.80 MEN1 (0.36) MEN1KMT2ASRCALDH1A1HTT
Nitrobenzene SCHEMBL7953615 0.73 NPSR1 (0.48) ITGA4ITGB7MEN1KMT2AALDH1A1
Acetic Acid SCHEMBL7951718 0.72 TACR1 (0.39) MEN1KMT2ASRCALDH1A1HTT
Nitrobenzene SCHEMBL9326043 0.67 ALDH1A1 (0.55) MEN1KMT2AALDH1A1NPSR1GLO1
Nitrobenzene SCHEMBL7949085 0.66 MAPT (0.49) ITGA4ITGB7MEN1KMT2AALDH1A1
Thymol SCHEMBL28080455 0.64 TRPA1 (0.78) MEN1KMT2ASRCALDH1A1HTT
Thymol SCHEMBL28146837 0.63 LMNA (0.60) MEN1KMT2ASRCALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255517-B1 6-SULFONYLOXYISOPROPENYL-M-CRESOL AND ESTERS Zee, Ok Pyo (KR) 2001-07-03 US disclosed