Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585344 | 0.91 | ABCB1 (0.52) | ABCB1METAP2METAP1PTGS2 | |
| SCHEMBL3913665 | 0.82 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL30849681 | 0.82 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL7809649 | 0.79 | ABCB1 (0.54) | ABCB1CYP2C19 | |
| SCHEMBL7942004 | 0.75 | PPARG (0.46) | — | |
| SCHEMBL30849672 | 0.75 | ABCB1 (0.48) | ABCB1CYP2C19 | |
| SCHEMBL9657320 | 0.75 | ABCB1 (0.48) | ABCB1CYP2C19 | |
| SCHEMBL9706052 | 0.73 | NPC1 (0.47) | CYP2C19 | |
| SCHEMBL1837302 | 0.73 | POLB (0.50) | ABCB1CYP2C19 | |
| SCHEMBL6535200 | 0.73 | PTGS2 (0.54) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0780361-B1 | Manufacturing method for aromatic carbonates | GEN ELECTRIC (US) | 2000-09-06 | — | — | EP | disclosed |
| EP-0779312-B1 | Manufacturing method for polycarbonate | GEN ELECTRIC (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0780361-A1 | Manufacturing method for aromatic carbonates | GENERAL ELECTRIC COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0779312-A2 | Manufacturing method for polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |