Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585351 | 0.91 | PPARG (0.46) | PPARGPPARARIPK1KDM4EBCAT2 | |
| SCHEMBL7809658 | 0.83 | RIPK1 (0.53) | PPARGPPARARIPK1KDM4EBCAT2 | |
| SCHEMBL2592053 | 0.78 | LMNA (0.53) | PPARGPPARARIPK1KDM4EBCAT2 | |
| SCHEMBL7942002 | 0.75 | ABCB1 (0.52) | — | |
| SCHEMBL31005082 | 0.73 | TAAR1 (0.48) | PPARGPPARARIPK1KDM4ELMNA | |
| SCHEMBL11050916 | 0.73 | TAAR1 (0.48) | PPARGPPARARIPK1KDM4ELMNA | |
| SCHEMBL31005083 | 0.73 | TAAR1 (0.48) | PPARGPPARARIPK1KDM4ELMNA | |
| SCHEMBL608097 | 0.73 | MTNR1A (0.44) | KDM4EHPGDHSD17B10MTNR1AMTNR1B | |
| SCHEMBL729676 | 0.73 | THRA (0.53) | PPARGPPARAMTNR1AMTNR1BNPSR1 | |
| SCHEMBL606944 | 0.73 | MTNR1A (0.44) | KDM4EHPGDHSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0780361-B1 | Manufacturing method for aromatic carbonates | GEN ELECTRIC (US) | 2000-09-06 | — | — | EP | disclosed |
| EP-0779312-B1 | Manufacturing method for polycarbonate | GEN ELECTRIC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5760156-A | Manufacturing method for polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0780361-A1 | Manufacturing method for aromatic carbonates | GENERAL ELECTRIC COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0779312-A2 | Manufacturing method for polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |