Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30887170 | 1.00 | LMNA (0.43) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL17357497 | 0.97 | LMNA (0.41) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL8399930 | 0.91 | NPC1 (0.45) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL7944222 | 0.84 | MAPT (0.50) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL30887114 | 0.84 | MAPT (0.50) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL1468002 | 0.82 | LMNA (0.60) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL29375339 | 0.82 | LMNA (0.60) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL5584199 | 0.82 | MAPT (0.48) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL31583281 | 0.82 | MAPT (0.48) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL30887227 | 0.81 | NPC1 (0.38) | LMNACNR1CNR2GPR55TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750011-B1 | Polysiloxanes as light stabilising agents | CIBA SC HOLDING AG (CH) | 2001-11-07 | — | — | EP | disclosed |
| US-5837792-A | MODIFIED POLYSILOXANES WITH HYDROXYPHENYLDIARYL-S-TRIAZINE GROUPS FOR LIGHT, HEAT AND OXYGEN STABILIZATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0750011-A1 | Polysiloxanes as light stabilising agents | Ciba SC Holding AG (CH) | 1996-12-27 | — | — | EP | disclosed |