SCHEMBL7942431

SCHEMBL7942431

CCc1cc(C(=O)OCCO)cc(C(C)(C)C)c1O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.45
ESR1 P03372 8/20 0.43
LMNA P02545 1/20 0.43
RECQL P46063 1/20 0.43
SERPINE1 P05121 4/20 0.42
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556848 0.93 SERPINE1 (0.50) HSPA5ESR1LMNARECQLSERPINE1
SCHEMBL7943043 0.90 LMNA (0.49) ESR1LMNARECQLSERPINE1AKR1C4
SCHEMBL7942545 0.89 ESR1 (0.41) ESR1SERPINE1AKR1C4AKR1C3AKR1C2
SCHEMBL8137558 0.89 ESR1 (0.55) HSPA5ESR1LMNARECQLSERPINE1
SCHEMBL7933960 0.87 ESR1 (0.43) ESR1LMNASERPINE1AKR1C4AKR1C3
SCHEMBL7942418 0.84 LMNA (0.46) ESR1LMNARECQLSERPINE1AKR1C4
SCHEMBL7943065 0.84 ESR1 (0.54) ESR1LMNARECQLSERPINE1AKR1C4
SCHEMBL7933964 0.83 ESR1 (0.47) ESR1LMNASERPINE1AKR1C4AKR1C3
SCHEMBL7933935 0.83 SLC29A1 (0.39) ESR1LMNA
SCHEMBL11615042 0.81 SERPINE1 (0.55) ESR1LMNARECQLSERPINE1AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed