Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933960 | 0.90 | ESR1 (0.43) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7942431 | 0.89 | HSPA5 (0.45) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7942418 | 0.88 | LMNA (0.46) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7942620 | 0.86 | ESR1 (0.54) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7933964 | 0.86 | ESR1 (0.47) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7940414 | 0.84 | SLC29A1 (0.38) | ESR1KDM4EALDH1A1GAAPKM | |
| SCHEMBL9556848 | 0.81 | SERPINE1 (0.50) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7933825 | 0.80 | KDM4E (0.48) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL3810025 | 0.78 | ALDH1A1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7943043 | 0.78 | LMNA (0.49) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |