Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640796 | 1.00 | IDO1 (0.49) | IDO1TDO2LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL8745681 | 0.85 | IDO1 (0.47) | IDO1TDO2LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL2245383 | 0.82 | LMNA (0.55) | IDO1TDO2LMNASMN1; SMN2HTT | |
| SCHEMBL334927 | 0.77 | SLC1A3 (0.64) | LMNASMN1; SMN2SLC1A3SLC1A1HTT | |
| SCHEMBL334926 | 0.77 | SLC1A3 (0.64) | LMNASMN1; SMN2SLC1A3SLC1A1HTT | |
| SCHEMBL735799 | 0.77 | SLC1A3 (0.64) | LMNASMN1; SMN2SLC1A3SLC1A1HTT | |
| SCHEMBL274968 | 0.76 | GPBAR1 (0.51) | SMN1; SMN2GAAGPBAR1 | |
| SCHEMBL5227458 | 0.76 | GPBAR1 (0.51) | SMN1; SMN2GAAGPBAR1 | |
| SCHEMBL11323275 | 0.75 | LMNA (0.51) | IDO1TDO2LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL794883 | 0.75 | LMNA (0.51) | IDO1TDO2LMNASMN1; SMN2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616079-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | University of Zürich (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034955-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | UNIVERSITY OF ZURICH (CH) | 2012-03-22 | — | — | WO | disclosed |