Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794256 | 0.85 | IDO1 (0.49) | IDO1TDO2LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL28640796 | 0.85 | IDO1 (0.49) | IDO1TDO2LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL7191584 | 0.81 | ALDH1A1 (0.47) | IDO1TDO2LMNASMN1; SMN2HTT | |
| SCHEMBL6449041 | 0.80 | CYP1A2 (0.46) | IDO1TDO2LMNASMN1; SMN2MEN1 | |
| SCHEMBL9797934 | 0.79 | CTSL (0.57) | IDO1TDO2 | |
| SCHEMBL9812665 | 0.78 | CTSK (0.50) | IDO1TDO2SMN1; SMN2 | |
| SCHEMBL148443 | 0.77 | GPBAR1 (0.46) | SMN1; SMN2GAAKMT2AL3MBTL1 | |
| SCHEMBL10628905 | 0.76 | CTSK (0.57) | — | |
| SCHEMBL16533444 | 0.76 | LMNA (0.60) | LMNASMN1; SMN2SLC1A3SLC1A1HTT | |
| SCHEMBL9810239 | 0.76 | CYP3A4 (0.55) | IDO1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546179-B1 | 4-O-(AMINOGLYCOSYL)- OR 4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXY-5,5-DIFLUOROSTREPTAMINE DERIVATIVE AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-5527781-A | AMINOGLYCOSIDE ANTIBIOTICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0259014-A2 | 5-Deoxy-5-fluorokanamycin B derivatives and processes for the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-03-09 | — | — | EP | disclosed |