Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366837 | 0.93 | LMNA (0.36) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2366844 | 0.93 | LMNA (0.36) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2366652 | 0.91 | LMNA (0.39) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2366647 | 0.91 | LMNA (0.39) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2366914 | 0.91 | EGLN1 (0.38) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2366911 | 0.91 | EGLN1 (0.38) | LMNAEGLN1KMT2AMEN1NTSR1 | |
| SCHEMBL2365683 | 0.88 | P2RX3 (0.38) | LMNAEGLN1KMT2AMEN1SLC6A7 | |
| SCHEMBL2365671 | 0.88 | P2RX3 (0.38) | LMNAEGLN1KMT2AMEN1SLC6A7 | |
| SCHEMBL2366699 | 0.87 | ALDH1A1 (0.41) | EGLN1KMT2AMEN1NTSR1ALDH1A1 | |
| SCHEMBL2366693 | 0.87 | ALDH1A1 (0.41) | EGLN1KMT2AMEN1NTSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050461-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | 田辺三菱製薬株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |