Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | APOL1 | O14791 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943694 | 0.88 | ELANE (0.46) | DPP4ALDH1A1ELANE | |
| SCHEMBL7997452 | 0.81 | TRPV1 (0.47) | SCN9APIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1688348 | 0.77 | SPHK1 (0.43) | KMT2ADPP4HTR1AHTR7ALDH1A1 | |
| SCHEMBL7944997 | 0.76 | DPP4 (0.40) | DPP4ELANEPIK3CA | |
| SCHEMBL20388035 | 0.76 | DPP4 (0.40) | DPP4ELANEPIK3CA | |
| SCHEMBL3726967 | 0.75 | DPP4 (0.42) | DPP4ELANE | |
| SCHEMBL17188738 | 0.75 | PIK3CA (0.42) | DPP4APOL1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL10069866 | 0.75 | EPHX2 (0.43) | KMT2A | |
| SCHEMBL1688344 | 0.74 | EPHX2 (0.42) | KMT2A | |
| SCHEMBL24051779 | 0.73 | ELANE (0.42) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |