Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 5/20 | 0.41 |
| ▸ | STAT5A | P42229 | 1/20 | 0.41 |
| ▸ | STAT5B | P51692 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942699 | 0.88 | THRB (0.46) | ELANEDPP4ALDH1A1 | |
| SCHEMBL10069866 | 0.81 | EPHX2 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL9551619 | 0.81 | ACE (0.47) | ELANEDPP4ERAP2ERAP1LNPEP | |
| SCHEMBL1688344 | 0.80 | EPHX2 (0.42) | — | |
| SCHEMBL1688348 | 0.80 | SPHK1 (0.43) | ELANEHCRTR2DPP4ALDH1A1 | |
| SCHEMBL7987507 | 0.80 | CNR2 (0.47) | RAB9AALDH1A1 | |
| SCHEMBL7935872 | 0.79 | ELANE (0.45) | ELANEHCRTR2RAB9A | |
| SCHEMBL20388035 | 0.78 | DPP4 (0.40) | ELANEDPP4ACE | |
| SCHEMBL7944997 | 0.78 | DPP4 (0.40) | ELANEDPP4ACE | |
| SCHEMBL26616459 | 0.78 | ERAP2 (0.47) | ERAP2ERAP1LNPEPACESTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |