Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987507 | 0.91 | CNR2 (0.47) | TRPV1NPC1RAB9ASMN1; SMN2KCNQ1 | |
| SCHEMBL7997391 | 0.90 | KCNQ1 (0.53) | NPC1RAB9ASMN1; SMN2KCNQ1LMNA | |
| SCHEMBL17188767 | 0.85 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL7997071 | 0.83 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KCNQ1LMNA | |
| SCHEMBL17188760 | 0.83 | UCHL1 (0.46) | TRPV1KCNQ1PIK3CAPIK3CDPIK3CG | |
| SCHEMBL7942699 | 0.81 | THRB (0.46) | SCN9APIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL17188788 | 0.77 | — | — | |
| SCHEMBL17188738 | 0.75 | PIK3CA (0.42) | PIK3CAPIK3CDPIK3CGPIK3CBPIK3C2B | |
| SCHEMBL7999807 | 0.75 | CNR2 (0.44) | TRPV1NPC1RAB9ASMN1; SMN2KCNQ1 | |
| SCHEMBL7943694 | 0.72 | ELANE (0.46) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |