Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508909 | 0.86 | KCNQ3 (0.37) | — | |
| SCHEMBL13567931 | 0.80 | NPSR1 (0.36) | ALDH1A1SLC6A4MAPT | |
| SCHEMBL1508787 | 0.80 | NPSR1 (0.36) | ALDH1A1SLC6A4MAPT | |
| SCHEMBL1508821 | 0.76 | HDAC11 (0.33) | ALDH1A1 | |
| SCHEMBL13567917 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SLC6A4MAPT | |
| SCHEMBL1509079 | 0.74 | PDE10A (0.34) | ALDH1A1MAPT | |
| SCHEMBL3831124 | 0.69 | NPSR1 (0.34) | ALDH1A1 | |
| SCHEMBL2487546 | 0.69 | NPSR1 (0.34) | ALDH1A1 | |
| SCHEMBL3831127 | 0.69 | NPSR1 (0.34) | ALDH1A1 | |
| SCHEMBL13567908 | 0.68 | ALDH1A1 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151069-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIRO[2.5]OCTANE RING STRUCTURE | 第一三共株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |