SCHEMBL7943273

SCHEMBL7943273

Cc1cc(C)c(Nc2c(C)cc(C)cc2C(C)C)c(C(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 19/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19629086 0.84 RAPGEF4 (0.46) RAPGEF4
SCHEMBL3352406 0.79 RAPGEF4 (0.58) RAPGEF4
SCHEMBL502929 0.77 RAPGEF4 (1.00) RAPGEF4
Hydrochloric Acid SCHEMBL812454 0.77 RAPGEF4 (0.35) RAPGEF4
Bromide SCHEMBL813884 0.77 RAPGEF4 (0.35) RAPGEF4
SCHEMBL17125221 0.74 LMNA (0.42) RAPGEF4
SCHEMBL1229146 0.73 LMNA (0.38) RAPGEF4
SCHEMBL18734563 0.72 RAPGEF4 (0.56) RAPGEF4
SCHEMBL8674689 0.71 LMNA (0.37) RAPGEF4
Hydrochloric Acid SCHEMBL813869 0.71 CARM1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316557-B1 FOR PRODUCING HIGH QUALITY, STEREOSPECIFIC POLYOLEFINS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-13 US disclosed
US-6255244-B1 OBTAINED BY CONTACTING A TRANSITION METAL COMPOUND, AN OXYGEN-CONTAINING COMPOUND TO FORM AN IONIC COMPLEX, AND AN ADSORBING SUBSTANCE DURING OR AFTER THE CONTACTING TREATMENT, THEN FOLLOWED BY REMOVING THE ADSORBING SUBSTANCE. IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-07-03 US disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed