Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925868 | 0.86 | MAPK1 (0.47) | — | |
| SCHEMBL812723 | 0.83 | GABRA1 (0.52) | — | |
| SCHEMBL18734563 | 0.81 | RAPGEF4 (0.56) | RAPGEF4 | |
| SCHEMBL5670018 | 0.81 | RAPGEF4 (0.40) | RAPGEF4 | |
| SCHEMBL7943273 | 0.79 | RAPGEF4 (0.61) | RAPGEF4 | |
| SCHEMBL14168981 | 0.79 | RAPGEF4 (0.75) | RAPGEF4 | |
| SCHEMBL12152328 | 0.78 | LMNA (0.40) | RAPGEF4 | |
| SCHEMBL12076480 | 0.78 | GABRA1 (0.43) | — | |
| SCHEMBL30406436 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL13535527 | 0.76 | GABRA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206107-B2 | Method for producing carboxylic acid and alcohol by hydrolysis of ester | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20140378692-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-12-25 | — | — | US | disclosed |
| JP-2010209027-A | PROCESS FOR PRODUCING ESTER BY DEHYDRATION CONDENSATION IN WATER | NAGOYA UNIV | 2010-09-24 | — | — | JP | disclosed |
| EP-1731498-B1 | METHOD FOR PRODUCING ESTER AND ESTERIFICATION CATALYST | INST NAGOYA IND SCIENCE RES (JP) | 2010-05-19 | — | — | EP | disclosed |
| EP-1731498-A1 | METHOD FOR PRODUCING ESTER AND ESTERIFICATION CATALYST | Nagoya Industrial Science Research Institute (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378692-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | ADH5, ADH1C, ADH1A | RAPGEF4 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.