Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.58 |
| ▸ | DRD4 | P21917 | 12/20 | 0.58 |
| ▸ | DRD2 | P14416 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980094 | 0.81 | CYP2D6 (0.60) | DRD3DRD4DRD2KMT2AMEN1 | |
| SCHEMBL11136336 | 0.79 | DRD4 (0.51) | DRD3DRD4DRD2KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL11220155 | 0.78 | DRD4 (0.50) | DRD3DRD4DRD2KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL10669369 | 0.77 | DRD2 (0.57) | DRD3DRD4DRD2KMT2AMEN1 | |
| SCHEMBL350525 | 0.76 | OPRL1 (0.65) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2013313 | 0.76 | DRD4 (0.53) | DRD3DRD4DRD2CYP3A4CYP2D6 | |
| SCHEMBL10226080 | 0.75 | OPRL1 (0.81) | DRD3DRD4KMT2ACYP3A4OPRM1 | |
| SCHEMBL22928541 | 0.74 | DRD3 (1.00) | DRD3DRD4DRD2KMT2AMEN1 | |
| SCHEMBL11206162 | 0.74 | OPRL1 (0.65) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL11199734 | 0.73 | OPRL1 (0.64) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255306-B1 | PSYCHOLOGICAL DISORDERS | MACOR JOHN E (US) | 2001-07-03 | — | — | US | disclosed |