Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032088 | 0.93 | OPRM1 (0.75) | OPRM1OPRK1OPRL1CYP2D6ADRA1D | |
| SCHEMBL8917214 | 0.85 | OPRM1 (0.68) | OPRM1OPRK1OPRL1CYP2D6KDM4E | |
| SCHEMBL31328459 | 0.84 | ADRA1D (0.55) | OPRM1OPRK1OPRL1CYP2D6ADRA1D | |
| SCHEMBL5315588 | 0.84 | HTR2B (0.53) | OPRM1OPRK1OPRL1CYP2D6KDM4E | |
| SCHEMBL19210848 | 0.83 | KDM4E (0.70) | CYP2D6KDM4EATMADRA1DSLC6A4 | |
| SCHEMBL9032327 | 0.83 | ADRA1D (0.69) | CYP2D6ADRA1DSLC6A4KCNH2 | |
| SCHEMBL6785509 | 0.82 | HDAC1 (0.67) | OPRM1OPRK1OPRL1KDM4EADRA1D | |
| Hydrochloric Acid SCHEMBL30908966 | 0.82 | ADRA1D (0.70) | CYP2D6ADRA1DSLC6A4KCNH2 | |
| SCHEMBL5359654 | 0.81 | KMT2A (0.62) | OPRM1OPRK1OPRL1ADRA1DCHRM4 | |
| SCHEMBL14306777 | 0.81 | ADRA1D (0.80) | CYP2D6KDM4EATMADRA1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255306-B1 | PSYCHOLOGICAL DISORDERS | MACOR JOHN E (US) | 2001-07-03 | — | — | US | disclosed |