Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.61 |
| ▸ | DNPEP | Q9ULA0 | 4/20 | 0.61 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.53 |
| ▸ | LAP3 | P28838 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941699 | 1.00 | ANPEP (0.61) | ANPEPDNPEPRNPEPLAP3RAB9A | |
| SCHEMBL19474113 | 1.00 | ANPEP (0.61) | ANPEPDNPEPRNPEPLAP3RAB9A | |
| Hydrochloric Acid SCHEMBL8054071 | 0.98 | ANPEP (0.59) | ANPEPDNPEPRNPEPLAP3RAB9A | |
| Hydrochloric Acid SCHEMBL8041160 | 0.98 | ANPEP (0.59) | ANPEPDNPEPRNPEPLAP3RAB9A | |
| SCHEMBL7943423 | 0.87 | ANPEP (0.49) | ANPEPDNPEPRNPEPLAP3DPP7 | |
| SCHEMBL7945922 | 0.87 | ANPEP (0.49) | ANPEPDNPEPRNPEPLAP3DPP7 | |
| SCHEMBL9140084 | 0.85 | USP2 (0.50) | ANPEPDNPEPDPP7SLC15A1TERT | |
| SCHEMBL9140089 | 0.85 | USP2 (0.50) | ANPEPDNPEPDPP7SLC15A1TERT | |
| SCHEMBL7936521 | 0.85 | DPP7 (0.50) | ANPEPDNPEPRNPEPLAP3DPP7 | |
| Hydrochloric Acid SCHEMBL8766670 | 0.83 | USP2 (0.48) | ANPEPDNPEPDPP7SLC15A1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | HERMES JEFFERY D | 2010-01-07 | — | — | US | disclosed |
| US-7504425-B2 | Compounds useful in the treatment of anthrax and inhibiting lethal factor | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | ANTXR2, SERPINB1, APAF1 | ANPEP 179/4885DNPEP 303/4885RNPEP 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.