Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943423 | 1.00 | ANPEP (0.49) | ANPEPDNPEPDPP7RRM1SLC15A1 | |
| SCHEMBL7936521 | 0.94 | DPP7 (0.50) | ANPEPDNPEPDPP7RRM1SLC15A1 | |
| SCHEMBL7943709 | 0.87 | ANPEP (0.61) | ANPEPDNPEPDPP7SLC15A1RNPEP | |
| SCHEMBL7941699 | 0.87 | ANPEP (0.61) | ANPEPDNPEPDPP7SLC15A1RNPEP | |
| SCHEMBL19474113 | 0.87 | ANPEP (0.61) | ANPEPDNPEPDPP7SLC15A1RNPEP | |
| Hydrochloric Acid SCHEMBL8054071 | 0.85 | ANPEP (0.59) | ANPEPDNPEPDPP7SLC15A1RNPEP | |
| Hydrochloric Acid SCHEMBL8041160 | 0.85 | ANPEP (0.59) | ANPEPDNPEPDPP7SLC15A1RNPEP | |
| SCHEMBL15623812 | 0.85 | ALDH1A2 (0.54) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL11921172 | 0.83 | KMT2A (0.50) | ANPEPDNPEPDPP7RRM1KISS1R | |
| SCHEMBL23802344 | 0.82 | DPP7 (0.43) | ANPEPDNPEPDPP7RRM1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | HERMES JEFFERY D | 2010-01-07 | — | — | US | disclosed |
| US-7504425-B2 | Compounds useful in the treatment of anthrax and inhibiting lethal factor | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | ANTXR2, SERPINB1, APAF1 | ANPEP 179/4885DNPEP 303/4885DPP7 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.