Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597349 | 0.89 | DGAT1 (0.56) | DGAT1CYP2C19KMT2A | |
| SCHEMBL2597461 | 0.87 | TSHR (0.37) | CYP2C19KMT2A | |
| SCHEMBL1785142 | 0.83 | CYP2C19 (0.36) | CYP2C19KMT2ALMNAHSD17B10PRKCA | |
| SCHEMBL733594 | 0.83 | PRKCA (0.43) | CYP2C19KMT2ALMNAHSD17B10PRKCA | |
| SCHEMBL23293628 | 0.81 | ALDH1A1 (0.36) | CYP2C19KMT2ALMNAHSD17B10HMGCR | |
| Hydrogen Peroxide SCHEMBL28451976 | 0.81 | PRKCA (0.42) | CYP2C19KMT2ALMNAHSD17B10HMGCR | |
| Carbamic Acid SCHEMBL29228025 | 0.80 | PRKCA (0.38) | CYP2C19KMT2ALMNAHSD17B10PRKCA | |
| SCHEMBL4381959 | 0.79 | HTT (0.34) | CYP2C19KMT2ALMNAHSD17B10 | |
| SCHEMBL5611254 | 0.79 | CYP2C19 (0.39) | CYP2C19KMT2ALMNAHSD17B10 | |
| SCHEMBL18293615 | 0.79 | HTT (0.34) | CYP2C19KMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448182-A | Aztreonam derivative and application thereof | 阿里萨制药有限公司 | 2020-07-24 | — | — | CN | disclosed |
| US-6331620-B1 | AS POLYMERIZATION CATALYSTS FOR PRODUCING STEREOSPECIFIC HOMOPOLYMER OR COPOLYMER OF ALPHA-OLEFINS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |