Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.36 |
| ▸ | PRKCG | P05129 | 3/20 | 0.36 |
| ▸ | PRKCB | P05771 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCH | P24723 | 3/20 | 0.36 |
| ▸ | PRKCI | P41743 | 3/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271277 | 0.76 | USP7 (0.71) | USP8USP7KDM4EHPGDALDH1A1 | |
| SCHEMBL13923619 | 0.75 | CHEK1 (0.38) | USP8USP7PPOXGSK3BGRM5 | |
| Phthalimide SCHEMBL3702599 | 0.75 | GSK3B (0.65) | USP8USP7GSK3BGRM5HPGD | |
| SCHEMBL23968840 | 0.74 | USP7 (0.75) | USP8USP7KDM4EHPGDALDH1A1 | |
| SCHEMBL1263254 | 0.73 | PPOX (0.38) | USP8USP7PPOXGSK3BGRM5 | |
| SCHEMBL2809485 | 0.73 | GRM5 (0.59) | PPOXGSK3BGRM5TDP1CYP3A4 | |
| SCHEMBL8834544 | 0.72 | EGFR (0.56) | GSK3BGRM5KDM4EHPGDALDH1A1 | |
| SCHEMBL13606492 | 0.72 | GSK3B (0.38) | USP8USP7PPOXGSK3BNPSR1 | |
| SCHEMBL9489040 | 0.70 | GSK3B (0.46) | USP8USP7GSK3BKDM4EHPGD | |
| SCHEMBL4961072 | 0.70 | USP8 (0.38) | USP8USP7KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315477-B2 | Materials having electron deficient moieties and methods of synthesizing thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150218115-A1 | MATERIALS HAVING ELECTRON DEFICIENT MOIETIES AND METHODS OF SYNTHESIZING THEREOF | NATIONAL SCIENCE FOUNDATION | 2015-08-06 | — | — | US | disclosed |
| US-6191307-B1 | Process for making benzoic acids | ALBEMARLE CORPORATION | 2001-02-20 | — | — | US | disclosed |
| US-4132711-A | Process for preparing nitriles | SUNTECH, INC. (US) | 1979-01-02 | — | — | US | disclosed |
| US-4057432-A | PHOTOGRAPHIC COUPLERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218115-A1 | MATERIALS HAVING ELECTRON DEFICIENT MOIETIES AND METHODS OF SYNTHESIZING THEREOF | NBAS, EMD, MPO | USP8 3662/4885USP7 4137/4885PPOX 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.