Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL217385 | 1.00 | HTR6 (0.32) | HTR6HTR2ASIGMAR1 | |
| Fluoride Ion SCHEMBL1130630 | 0.97 | HTR6 (0.32) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL216942 | 0.83 | SIGMAR1 (0.31) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6840561 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7945843 | 0.79 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL216949 | 0.79 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29556619 | 0.79 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL5853720 | 0.76 | SIGMAR1 (0.30) | SIGMAR1 | |
| Fluoride Ion SCHEMBL1130440 | 0.75 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6724663 | 0.75 | HTR6 (0.31) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324801-A | Without ring opening; aluminoxane and a steriorigid metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | claimed |
| US-6169052-B1 | CATALYST SYSTEM COMPRISING ALUMINOXANE AND A STEREORIGID METALLOCENE COMPOUND | TARGOR GMBH (DE) | 2001-01-02 | — | — | US | disclosed |
| US-5324801-A | Without ring opening; aluminoxane and a steriorigid metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | disclosed |