SCHEMBL7943944

SCHEMBL7943944

C=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218232 0.86 HTR2A (0.35) HTR6HTR2A
SCHEMBL8561321 0.81 HTR6 (0.33) HTR6HTR2A
SCHEMBL7946949 0.78 SLC22A2 (0.38) HTR2A
SCHEMBL8733906 0.78 SLC22A2 (0.31)
SCHEMBL7935566 0.77 SLC22A2 (0.33) HTR6HTR2A
SCHEMBL7943229 0.77 SLC22A2 (0.30)
SCHEMBL7611904 0.77 CYP2D6 (0.33)
Hydrochloric Acid SCHEMBL7108220 0.77 KDM4E (0.31)
Hydrochloric Acid SCHEMBL5911761 0.77
SCHEMBL6916127 0.77 SLC22A2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US claimed
US-6255508-B1 COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST TARGOR GMBH (DE) 2001-07-03 US disclosed
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US disclosed