SCHEMBL218232

SCHEMBL218232

C=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943944 0.86 HTR6 (0.30) HTR2AHTR6
SCHEMBL3380394 0.80 HTR2A (0.35) HTR2AHTR6
SCHEMBL9222381 0.80 HTR2A (0.35) HTR2AHTR6
SCHEMBL7947949 0.80 HTR6 (0.39) HTR2AHTR6
SCHEMBL7095115 0.79 HTR6 (0.33) HTR2AHTR6
SCHEMBL28978370 0.79 HTR6 (0.33) HTR2AHTR6
SCHEMBL30577433 0.79 HTR2A (0.40) HTR2AHTR6
Hydrochloric Acid SCHEMBL2901254 0.78 HTR2A (0.34) HTR2AHTR6
SCHEMBL9280884 0.77 HTR6 (0.33) HTR2AHTR6
SCHEMBL2763485 0.77 SIGMAR1 (0.35) HTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US claimed
JP-5043624-A None JP disclosed
US-12491207-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability VANELTIX PHARMA, INC. (US) 2025-12-09 US disclosed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 US disclosed
US-11491179-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability URIGEN PHARMACEUTICALS, INC. (US) 2022-11-08 US disclosed
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2021-09-16 US disclosed
EP-3609483-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY Urigen Pharmaceuticals, Inc. (US) 2020-02-19 EP disclosed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
WO-2018191412-A9 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2019-05-31 WO disclosed
WO-2018191412-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2018-10-18 WO disclosed
EP-0566349-A2 Process for producing alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-10-20 EP disclosed
US-5252677-A Epoxy, hydroxy or sulfonic acid end groups MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-10-12 US disclosed
EP-0553491-A1 Catalyst for polymerization of olefins and process for production of olefin polymers TOSOH CORPORATION (JP) 1993-08-04 EP disclosed
US-5225501-A Transition metal compound and alumoxane catalyst MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-06 US disclosed
JP-H0543624-A PRODUCTION OF MINUTE POLYPROPYLENE PARTICLE MITSUBISHI PETROCHEM CO LTD 1993-02-23 JP disclosed
EP-0512741-A1 Process for producing a propylene random copolymer MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-11 EP disclosed
EP-0511846-A1 Aminated olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-04 EP disclosed
EP-0487278-A2 Functionalized olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-27 EP disclosed
US-5003019-A Radiation transparent, heat resistant, solvent resistant copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-03-26 US disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12491207-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885
US-11491179-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.