Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12368206 | 0.88 | NPC1 (0.67) | KCNMA1HPGDALOX15CES2GALR3 | |
| SCHEMBL9775415 | 0.84 | HDAC1 (0.56) | KCNMA1HPGDMAPTGAAKMT2A | |
| SCHEMBL17407572 | 0.83 | KMT2A (0.55) | KCNMA1HPGDALOX15CES2GALR3 | |
| Dibromsalan SCHEMBL29496335 | 0.82 | PLAU (0.73) | HPGDALOX15CES2GALR3CYP1A2 | |
| Dibromsalan SCHEMBL646973 | 0.82 | PLAU (0.73) | HPGDALOX15CES2GALR3CYP1A2 | |
| Bromocyl SCHEMBL678320 | 0.81 | HPGD (0.67) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL22394778 | 0.79 | MEN1 (0.51) | KCNMA1HPGDALOX15CES2GALR3 | |
| SCHEMBL30343477 | 0.79 | TMPRSS4 (0.67) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL330113 | 0.79 | TMPRSS4 (0.67) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL7517172 | 0.79 | PLAU (0.50) | KCNMA1HPGDALOX15CES2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255298-B1 | USING AN AROMATIC AMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2001-07-03 | — | — | US | claimed |
| US-6255298-B1 | USING AN AROMATIC AMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2001-07-03 | — | — | US | disclosed |