SCHEMBL330113

SCHEMBL330113

O=C(Nc1ccccc1)c1cc(Br)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMPRSS4 Q9NRS4 2/20 0.67
PLAU P00749 2/20 0.65
F2 P00734 1/20 0.65
F10 P00742 1/20 0.65
PLAT P00750 1/20 0.65
HSPD1 P10809 1/20 0.65
HSPE1 P61604 1/20 0.65
P2RX1 P51575 1/20 0.65
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
HPGD P15428 2/20 0.64
KDM4E B2RXH2 1/20 0.64
LMNA P02545 1/20 0.64
TP53 P04637 1/20 0.64
HTT P42858 1/20 0.64
HSD17B10 Q99714 1/20 0.64
ALOX15 P16050 2/20 0.63
F12 P00748 1/20 0.58
POLB P06746 1/20 0.57
CYP1A2 P05177 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30343477 1.00 TMPRSS4 (0.67) TMPRSS4PLAUF2F10PLAT
Dibromsalan SCHEMBL29211119 0.97 PLAU (0.66) TMPRSS4PLAUF2F10PLAT
Dibromsalan SCHEMBL29496335 0.90 PLAU (0.73) TMPRSS4PLAUF2F10PLAT
Dibromsalan SCHEMBL646973 0.90 PLAU (0.73) TMPRSS4PLAUF2F10PLAT
SCHEMBL9967909 0.85 HSPD1 (0.67) HSPD1HSPE1P2RX1MEN1KMT2A
Bromochlorosalicylanilide SCHEMBL152257 0.84 P2RX1 (0.77) TMPRSS4PLAUF2F10PLAT
SCHEMBL23825504 0.83 SORT1 (0.74) HSPD1HSPE1F12CYP2C9
SCHEMBL29980628 0.83 SORT1 (0.74) HSPD1HSPE1F12CYP2C9
SCHEMBL330366 0.83 P2RX1 (0.78) TMPRSS4HSPD1HSPE1P2RX1
SCHEMBL10967705 0.83 MEN1 (0.64) PLAUF2F10PLATHSPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319056-A1 METHODS FOR TREATING CANCER UNIV INDIANA TRUSTEES (US) 2025-10-16 US disclosed
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-20250026741-A1 INHIBITORS OF THE ONCOGENIC SHP2 PHOSPHATASE AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2025-01-23 US disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed
US-20210395210-A1 INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2021-12-23 US disclosed
US-20210395210-A1 INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2021-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
US-20030176530-A1 Antimicrobial contact lens case LINDLEY KAREN FRANCES (US) 2003-09-18 US disclosed
WO-2003049776-A1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2003-06-19 WO disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
WO-2001070189-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS UNILEVER PLC (GB) 2001-09-27 WO disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 US disclosed
WO-1999035911-A1 ANTIMICROBIAL TOOTHBRUSH UNILEVER PLC (GB) 1999-07-22 WO disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395210-A1 INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS HSP90B1, HSP90AB1, HSP90AB2P TMPRSS4 3982/4885PLAU 2952/4885F2 4686/4885
US-20250026741-A1 INHIBITORS OF THE ONCOGENIC SHP2 PHOSPHATASE AND USES THEREOF PTPN18, PTPN7, PTPN1 TMPRSS4 2060/4885PLAU 3807/4885F2 4871/4885
US-20250319056-A1 METHODS FOR TREATING CANCER HSP90AB1, HSP90B1, HSP90AB2P TMPRSS4 3361/4885PLAU 1363/4885F2 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.