SCHEMBL9775415

SCHEMBL9775415

O=C(Nc1cc(Br)ccc1O)c1cc(C(=O)Nc2cc(Br)ccc2O)cc(C(=O)Nc2cc(Br)ccc2O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.56
MEN1 O00255 7/20 0.55
KMT2A Q03164 7/20 0.55
HPGD P15428 4/20 0.55
MAPT P10636 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
RAB9A P51151 3/20 0.55
ACLY P53396 1/20 0.53
SNCA P37840 1/20 0.51
LMNA P02545 3/20 0.51
KCNMA1 Q12791 4/20 0.50
NPC1 O15118 1/20 0.50
HTT P42858 1/20 0.50
GAA P10253 1/20 0.50
HDAC2 Q92769 1/20 0.50
PABPC1 P11940 1/20 0.49
DUSP3 P51452 1/20 0.49
PTPN5 P54829 1/20 0.49
PTPN11 Q06124 1/20 0.49
EIF4H Q15056 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943952 0.84 KCNMA1 (0.60) MEN1KMT2AHPGDMAPTSMN1; SMN2
SCHEMBL14243236 0.82 GPR35 (0.59) HDAC1MEN1KMT2AMAPTRAB9A
SCHEMBL22394778 0.81 MEN1 (0.51) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL2325682 0.79 SMN1; SMN2 (0.57) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL3869658 0.79 KMT2A (0.50) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL31469972 0.78 TGM2 (0.59) HDAC1MAPTSNCALMNATOP1
SCHEMBL17544218 0.78 HDAC1 (0.49) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL9775410 0.78 KCNMA1 (0.78) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL27188295 0.76 HDAC1 (0.51) HDAC1MEN1KMT2AHPGDMAPT
SCHEMBL24251938 0.75 MEN1 (0.47) HDAC1MEN1KMT2AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0373690-A2 Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain ENICHEM S.p.A. (IT) 1990-06-20 EP claimed
US-5049644-A Self-extinguishing ENICHEM TECNORESINE S.P.A. (IT) 1991-09-17 US disclosed
EP-0373690-A2 Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain ENICHEM S.p.A. (IT) 1990-06-20 EP disclosed