SCHEMBL79441

SCHEMBL79441

BrCCCCCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
SIGMAR1 Q99720 9/20 0.58
MAOA P21397 1/20 0.56
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
HDAC1 Q13547 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624612 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL854090 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL1773132 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL7612611 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL7563162 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL11806608 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL2404356 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL2162933 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL17027772 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT
SCHEMBL3310359 1.00 TDP1 (0.64) TDP1SIGMAR1MAOAMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN claimed
CN-106398080-A Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof 北京化工大学 2017-02-15 CN claimed
JP-10237096-A None JP disclosed
CN-120682625-B Wear-resistant flame-retardant cable and preparation method thereof 西部电缆陕西有限公司 2026-02-06 CN disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
CN-120682625-A Wear-resistant flame-retardant cable and preparation method thereof 西部电缆陕西有限公司 2025-09-23 CN disclosed
EP-4551566-A1 NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS Les Laboratoires Servier (FR) 2025-05-14 EP disclosed
CN-119816491-A New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2025-04-11 CN disclosed
US-20240287019-A1 T-TYPE CALCIUM CHANNEL BLOCKER FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2024-08-29 US disclosed
WO-2024140595-A1 TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 珂阑(上海)医药科技有限公司 2024-07-04 WO disclosed
CN-118255685-A Tricyclic compound, pharmaceutical composition and application thereof 珂阑(上海)医药科技有限公司 2024-06-28 CN disclosed
EP-0061800-A1 Anti SRS-A carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them FISONS plc (GB) 1982-10-06 EP disclosed
EP-0049981-A1 Valienamine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-04-21 EP disclosed
US-4324796-A HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-04-13 US disclosed
EP-0044940-A1 Amino-desoxy-1.4;3.6-dianhydro-hexite nitrates, processes for their preparation and pharmaceutical compositions Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP disclosed
US-4265891-A PROSTAGLANDINS, BRONCHODILATORS, PLATELET AGGREGATION INHIBITORS GLAXO GROUP LIMITED (GB) 1981-05-05 US disclosed
US-4262128-A HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES BURROUGHS WELLCOME CO. (US) 1981-04-14 US disclosed
EP-0025192-A2 Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1981-03-18 EP disclosed
US-4204068-A Nitrogen heterocycles BURROUGHS WELLCOME CO. (US) 1980-05-20 US disclosed
US-4153606-A Process for the production of thiazoline-(3) compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX TDP1 2093/4885SIGMAR1 426/4885MAOA 3647/4885
US-20240287019-A1 T-TYPE CALCIUM CHANNEL BLOCKER CACNA1G, CACNA1I, CACNA1H TDP1 3610/4885SIGMAR1 2729/4885MAOA 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.