Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624612 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL1773132 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL7612611 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL7563162 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL11806608 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL2404356 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL2162933 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL79441 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL17027772 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT | |
| SCHEMBL3310359 | 1.00 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106398080-A | Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof | 北京化工大学 | 2017-02-15 | — | — | CN | claimed |
| CN-113527341-A | Alkane soluble tetrakis (pentafluorophenyl) borate and preparation method and application thereof | 中国石油天然气股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-106398080-B | A kind of ammonium cross-linking type block copolymer/graphene composite material and preparation method thereof | 北京化工大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-106398080-A | Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof | 北京化工大学 | 2017-02-15 | — | — | CN | disclosed |
| EP-2740724-B1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO PHARMACEUTICAL CO (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9085523-B2 | Compound for treating cartilage disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| EP-2432817-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2015-02-11 | — | — | EP | disclosed |
| US-20140296485-A1 | ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY | PNC BANK, NATIONAL ASSOCIATION | 2014-10-02 | — | — | US | disclosed |
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-06-19 | — | — | US | disclosed |
| EP-2740724-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO Pharmaceutical Co., Ltd. (JP) | 2014-06-11 | — | — | EP | disclosed |
| WO-2010135701-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORATION (US) | 2010-11-25 | — | — | WO | disclosed |
| EP-0637580-B1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5817775-A | HYDROFORMYLATION CATALYST | CELANESE INTERNATIONAL CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1997030018-A1 | 2,2-DIFLUOROALKANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1997-08-21 | — | — | WO | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0153403-A4 | CHEMICAL COMPOUNDS. | MALLINCKRODT INC (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0153403-A1 | CHEMICAL COMPOUNDS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-09-04 | — | — | EP | disclosed |
| WO-1985000753-A1 | CHEMICAL COMPOUNDS | MALLINCKRODT, INC. (US) | 1985-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | COL2A1, COL1A1, ADAMTS1 | TDP1 2713/4885SIGMAR1 3831/4885MAOA 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.