Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264880 | 0.84 | ALDH1A1 (0.46) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL24651223 | 0.83 | KCNH2 (0.42) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL27862075 | 0.82 | ALDH1A1 (0.46) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL3749720 | 0.80 | ALDH1A1 (0.57) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL5800011 | 0.80 | ALDH1A1 (0.57) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL859610 | 0.79 | KCNH2 (0.44) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| Hydrochloric Acid SCHEMBL28270652 | 0.79 | ALDH1A1 (0.56) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| SCHEMBL29892593 | 0.79 | KCNH2 (0.44) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| Hydrochloric Acid SCHEMBL28797396 | 0.79 | ALDH1A1 (0.56) | KCNH2ALDH1A1PRMT5WDR77F2 | |
| Hydrochloric Acid SCHEMBL29893284 | 0.77 | KCNH2 (0.43) | KCNH2ALDH1A1PRMT5WDR77F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246907-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 山东大学 | 2022-12-01 | — | — | WO | disclosed |
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |
| US-20080096912-A1 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC PYRROLIDINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096912-A1 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC PYRROLIDINE DERIVATIVES | IDO1, IDO2, INMT | KCNH2 1977/4885ALDH1A1 2096/4885PRMT5 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.