Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 19/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 18/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 14/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.66 |
| ▸ | CASP1 | P29466 | 12/20 | 0.64 |
| ▸ | CASP7 | P55210 | 10/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | USP2 | O75604 | 11/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945962 | 0.94 | CYP1A2 (0.59) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7946753 | 0.89 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7945959 | 0.88 | PDE4B (0.51) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7945984 | 0.86 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7938295 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7944785 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7938050 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7938047 | 0.84 | CYP1A2 (0.56) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7944641 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL7949559 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |