Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 19/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.51 |
| ▸ | CASP1 | P29466 | 10/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.48 |
| ▸ | CASP7 | P55210 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947917 | 0.89 | PDE4B (0.51) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7946067 | 0.87 | PDE4B (0.57) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7944623 | 0.86 | ALDH1A1 (0.66) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7947571 | 0.86 | PDE4B (0.47) | PDE4B | |
| SCHEMBL7938164 | 0.82 | PDE4B (0.42) | CLK4PDE4B | |
| SCHEMBL7945962 | 0.81 | CYP1A2 (0.59) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7944647 | 0.78 | MTOR (0.53) | KMT2APDE4B | |
| SCHEMBL7947184 | 0.77 | CYP1A2 (0.45) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7938416 | 0.77 | CYP1A2 (0.50) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 | |
| SCHEMBL7946753 | 0.75 | ALDH1A1 (0.52) | CYP1A2ALDH1A1CYP3A4HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |